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International Conference on Genetic Disorders and Gene Therapy, will be organized around the theme “”

ICGDTE 2021 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in ICGDTE 2021

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Genetics is the inheritance analysis. Heredity is a biological process in which the parent transmits those genes to their children or offspring. Each child inherits genes from both their biological parents and, in exchange, expresses specific traits. Some of these characteristics may be physical, e.g. hair and  eye colour, skin colour, etc. On the other hand, certain genes may also carry the risk of certain diseases and disorders that can spread to their offspring from parents.



 


  • Track 1-1Alleles
  • Track 1-2Genetic drift
  • Track 1-3Genome

Gene Therapy  basically involves the introduction or alteration of genetic material within a cell or organism with an intention of curing the disease. Both cell therapy and gene therapy are overlapping fields of biomedical research with the goals of repairing the direct cause of Genetic diseases in DNA or cellular population respectively, the discovery of recombinant DNA technology in the 1970s provided tools to efficiently develop gene therapy. Scientists use these techniques to readily manipulate viral genomes, isolate genes and identify mutations involved in human disease, characterize and regulate gene expressions, and engineer various viral and non-viral vectors. Various long-term treatments for anaemia, haemophilia, cystic fibrosis, muscular dystrophy, Gauscher’s disease, lysosomal storage diseases, cardiovascular  diseases, diabetes and diseases of bones and joints are resolved through successful gene therapy


  • Track 2-1Gene replacement therapy
  • Track 2-2Genetic disease

Customary methods for quality treatment fuse transfection. It twisted up evidently inefficient and confined fundamentally in light of transport of value into at present duplicating cells in-vitro. Quality treatment utilizes the transport of DNA into cells by techniques for vectors, for instance, natural nanoparticles or viral vectors and non-viral methodologies. The Several sorts of diseases vectors used as a piece of value treatment are retrovirus, adenovirus, adeno-related contamination and herpes simplex contamination. While other recombinant viral vector structures have been delivered, retroviral vectors remain the most surely understood vector system for quality treatment traditions and most prominent application in view of their undeniable significance as the essential vectors made for powerful quality treatment application and the soonest phases of the field of value treatment.


 


  • Track 3-1Antibodies
  • Track 3-2Antigens
  • Track 3-3Adult Stem Cells

Nano therapy is a Nano medicine branch that involves using nanoparticles to deliver a drug to a specific target body position to treat the disease through a process called targeting. This technique has become more popular compared to conventional approaches because it provides high precision when it comes to the delivery of therapeutic formulations. There is no targeting for conventional chemotherapy, which means that the drug is merely carried by the circulatory system until it enters and works on the affected part of the body.

  • Passive Targeting

  • Active Targeting



 


  • Track 4-1Nanotechnology
  • Track 4-2Nanodiagnosis
  • Track 4-3Nanoparticles

Human genetics  is study for Analysis of the parent's succession of characteristics. In human heritage as no fundamental way differs from that in other organisms. Human heredity research occupies a key genetic role. Much of this fascination derives from a deep desire to know who and why human beings are as they are. In a more practical way, Understanding human inheritance is critical in the prediction, diagnosis and treatment of genetic diseases. The quest to establish human health's genetic basis has given rise to the medical genetics industry. Medicine has generally given emphasis and purpose to human genetics, so it is often considered interchangeable with the terms of clinical genetics and human genetics.



 


  • Track 5-1human genetic diseases
  • Track 5-2polygenic

Fortunately, with no medical problems or birth defects, most children are born healthy. Nevertheless, some children are born with differences in body structure, brain development, or body chemistry that may lead to problems with health, development, school performance, and/or social interaction. Pediatric geneticists were trained to identify the causes and history of these diseases. They may suggest tests and treatments that may help you understand and take care of the condition of your child. Pediatric geneticists can also help families understand whether certain disorders are inherited (from genes) and provide screening to family members who may be at risk of having children with similar problems.

  • Birth defects

  • Down syndrome

  • Fetal alcohol syndrome

  • Inborn errors of metabolism

  • Familial or hereditary problems

  • Short or tall stature



 


  • Track 6-1Dominant
  • Track 6-2Homozygous
  • Track 6-3Genotype
  • Track 6-4Genetic predisposition

Cancer is a genetic problem where normal cell enhancement regulation is lost. Now, cancer biology is one of the fastest-growing cell differentiating abilities. At the nuclear level, a mutation(s) of DNA causes cancer, resulting in the development of twisted cells. The increasing dimension of these changes is guarded and occurs in external cells. In any case, the germ line is secured by a couple of individuals. The mutation(s) occurs in two cell characteristics classes on cogeneses and the characteristics of the tumour silencer. Tumour silencer characteristics monitor cell division and extension camouflage under standard conditions. Changes in these characteristics lead to unregulated cell replication which results in tumours with odd cell cycles and growth of tumours. The features of the tumour silencer contribute to the disease by inactivating limit Biogenesis Cancer cytogenetic



 


  • Track 7-1Chromosomes
  • Track 7-2Family Tree

Genes are heredity form squares. They're transferred from one parent to another. We carry the DNA, the instructions to produce proteins. The proteins do the vast majority of cell function. We transfer particles from one place to the next, form structures, isolate toxins, and perform various other support tasks. At times there is a change, a value improvement, or gene modification. The conversion changes the criteria of the quality to make a protein, so the protein does not function properly or is completely missing.

  • Multifactorial disorder

  • Chromosomal disorder



 


  • Track 8-1cystic fibrosis
  • Track 8-2Marfan syndrome
  • Track 8-3sickle cell anemia

Genetics in Health and Disease in which therapy utilizes genetics, imaging and biological indicators to understand predisposition to disease, what constitutes health during childhood and throughout the life course. Gene and Protein Function are used to develop tools, skills and resources to elucidate gene function and to inform development of new therapies using state-of the-art technologies. Personalised Medicine and Patient benefit is considered to ensure basic science discoveries of disease mechanisms and patient’s genomes are used to produce best effect to improve patients’ lives which include better diagnostics, identification of biomarkers and targeting of therapies.

  • Gene Therapy and Genetic Engineering

  • Somatic Gene Therapy

  • Germ Line Gene Therapy

  • Cell Cancer Immunotherapy

  • Somatic Cell Nuclear Transfer (SCNT)



 


  • Track 9-1single gene
  • Track 9-2Rett syndrome
  • Track 9-3Prader-willi syndrome

Gene Therapy is used to treat inherited Muscular disordercardiovascular disorder, HIV, cancer etc. In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or as a way for the donor's immune system to provoke immunity against some types of cancer and blood-related diseases, such as leukaemia. Cellular Therapy is internationally recognized for its novel approaches in treating blood related disorders like leukaemia, lymphoma, myeloma, and other life-threatening diseases. The stem cell transplantation of hematopoietic stem cells (HSCT) in which the allogeneic hematopoietic stem cells are harvested from healthy donors of same species and autologous stem cell from the patient itself. Both therapies use high dosage cytotoxic  medication  in order to induce higher remission rates against malignant diseases. Autologous HSCT preferably used in relapsed malignant high-grade lymphoma and Allogeneic HSCT preferred for therapeutic effect against acute leukaemia with unfavourable prognosis in a high percentage of patients. The Recent developments based on the expansion of the donor pool for allogeneic stem cells in order to reduce dosage as well as chemotherapeutic toxicity of allogeneic transplantation with sustainable anti-leukaemia efficacy

  • Neurological Disorder

  • Blindness Vision Impairment

  • Wound Healing

  • Cancer

  • HIV



 


  • Track 10-1Retroviruses
  • Track 10-2Adenoviruses
  • Track 10-3Herpes simplex

Genome editing with engineered nucleases (GEEN) is emergent type of Genetic Engineering. GEEN is the technology in which DNA is inserted, deleted or replaced in the genome. The emergence of highly versatile genome-editing technologies has provided investigators with the ability to rapidly and economically introduce sequence-specific modifications into the genomes of a broad spectrum of cell types and organisms. It also promotes various changes in sub cellular level. Genome Editing itself also holds tremendous potential for treating the underlying various idiopathic genetic causes of certain diseases. The core technologies now most commonly used techniques to facilitate genome editing are clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription activator-like effector nucleases (TALENs), zinc-finger nucleases (ZFNs), and homing endonucleases or mega nucleases.

  • Stem cell and cellular therapies

  • Cell therapy: clinical trials

  • Paediatrics’ and Genetics

  • Market and Future Prospects of Gene Therapy

  • Gene Editing and CRISPR Based Technologies



 


  • Track 11-1meganucleases
  • Track 11-2Gene targeting

Genomics  is genomics research, the whole arrangement of hereditary material within a form of life. Genomics involves the sequencing and analysis of genomes. Genomics is also concerned about the structure, ability, analysis and advancement of genomes. In contrast to the hereditary quality, which refers to the investigation of the individual qualities and their parts of the heritage, genome.

  • Functional genomics

  • Structural genomics

  • Metagenomics

  • Genomic medicine

  • Synthetic biology and bioengineering



 


  • Track 12-1 Computational genomics
  • Track 12-2Comparative genomics
  • Track 12-3Functional genomics

Functionality of biomaterials for these forms is depends upon the chemical reaction such as localized or systemic response at the surface tethered moieties or encapsulated therapeutic factors such as drugs, genes, cells, growth factors, hormones and other active agents to specific target sites. The application of functional biomaterials is rehabilitation, reconstruction, regeneration, repair, ophthalmic applications and act as therapeutic  solutions. It has the property of biocompatibility and produce inertness response to the tissue.   The biomaterial-m ed iated  gene therapy aim to use polymeric gene therapy systems to halt the progression of neuron loss through neuro-protective routes and it combine stem cell therapy and biomaterial delivery system in order to enhance regeneration or repair after ischemic injury.

  • Bio fabrication and Bone Tissue

  • Regeneration Manufacturing Challenges for Regenerative Medicine

  • Cardiac Progenitor Cells

  • Mesenchymal Cells



 


  • Track 13-1CRISPR gene editing
  • Track 13-2Organ transplants
  • Track 13-3Bone marrow transplantation